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Prescribing & DEA Roadmap

Missouri Registered Nurse Prescriptive authority

Separate professional authority, state registration and federal DEA steps.

Last researched

Source-linked research. Check the conditions for each requirement and confirm your circumstances with the board.

Use the boxes to track your preparation. Checking an item does not verify compliance.

Who may prescribe

  • Missouri collaborative-practice materials do not show an RN-alone prescriptive right; the supplied evidence instead limits any delegation to an RN who is also an APRN.

    Applies when: For Missouri Registered Nurse prescriptive authority.

    Source evidence
    1. 1. revisor.mo.gov ↗
      Collaborative practice arrangements, which shall be in writing, may delegate to a registered professional nurse the authority to administer, dispense or prescribe drugs and provide treatment if the registered professional nurse is an advanced practice registered nurse

  • The supplied rule text says an RN under collaborative practice is not authorized for medical diagnosis.

    Applies when: For Missouri RN practice under a collaborative practice arrangement.

    Source evidence
    1. 1. sos.mo.gov ↗
      Nothing in these rules shall be construed to permit medical diagnosis of any condition by an RN pursuant to a collaborative practice arrangement.

License and education prerequisites

  • Prescribing may be delegated to a registered professional nurse only if the nurse is an APRN as defined in section 335.016.

    Applies when: For Missouri collaborative-practice prescribing delegation to an RN.

    Source evidence
    1. 1. revisor.mo.gov ↗
      may delegate to a registered professional nurse the authority to administer, dispense or prescribe drugs and provide treatment if the registered professional nurse is an advanced practice registered nurse as defined in subdivision (2) of section 335.016

Collaboration and supervision

  • Collaborative practice arrangements must be in writing, and the RN/APRN work must match each professional’s skill, training, education, and competence.

    Applies when: For Missouri collaborative practice arrangements involving prescribing delegation.

    Source evidence
    1. 1. revisor.mo.gov ↗
      Collaborative practice arrangements, which shall be in writing
    2. 2. revisor.mo.gov ↗
      Engage in collaborative practice consistent with each professional's skill, training, education, and competence;

  • The collaborating physician must determine and document at least a one-month period of continuous presence before the APRN practices where the physician is not continuously present.

    Applies when: For covered Missouri APRN collaborative practice settings.

    Source evidence
    1. 1. revisor.mo.gov ↗
      completion of at least a one-month period of time during which the advanced practice registered nurse shall practice with the collaborating physician continuously present before practicing in a setting where the collaborating physician is not continuously present

State controlled-substance authority

  • Missouri BNDD regulates legitimate medical controlled substance activities, and Missouri state-level controlled substance registration applications are online only.

    Applies when: For Missouri controlled-substance authority separate from DEA.

    Source evidence
    1. 1. health.mo.gov ↗
      tasked with regulating legitimate medical controlled substance activities performed by licensed medical professionals and entities within the State of Missouri.
    2. 2. health.mo.gov ↗
      applications for a Missouri state-level controlled substance registration can only be submitted online.

Federal DEA requirements

  • DEA registration is contingent on state authorization, and a separate DEA registration is required at each principal place of business or professional practice.

    Applies when: For Missouri practitioners seeking federal controlled-substance registration.

    Source evidence
    1. 1. deadiversion.usdoj.gov ↗
      DEA's authority to register practitioners to dispense (including to prescribe) controlled substances is contingent, in part, upon the applicant's authorization in the state in which he or she practices
    2. 2. deadiversion.usdoj.gov ↗
      The Controlled Substances Act requires a separate registration at each principal place of business or professional practice

  • A practitioner who never plans to administer, dispense, or prescribe a controlled substance does not need DEA registration.

    Applies when: General federal rule stated in DEA guidance.

    Source evidence
    1. 1. deadiversion.usdoj.gov ↗
      I am a practitioner, but I never plan on administering, dispensing, or prescribing a controlled substance. Must I have a DEA registration? Answer: No.

Training and monitoring †

  • †

    Could not confirm from the available official evidence.

  • DEA says it is recommended that each practitioner keep a record of training certificates or other materials documenting completion.

    Applies when: Advisory DEA guidance for covered practitioners.

    Source evidence
    1. 1. deadiversion.usdoj.gov ↗
      It is recommended that each practitioner keep a record of training certificates or other materials documenting completion.

Fees and renewals

  • License renewal for a professional nurse is biennial, occurring on odd-numbered years, and the license expires on April 30 of each odd-numbered year.

    Applies when: For Missouri professional nurse renewal scheduling only.

    Source evidence
    1. 1. sos.mo.gov ↗
      License renewal for a professional nurse and an APRN shall be biennial, occurring on odd-numbered years and the license shall expire on April 30 of each odd-numbered year.

Applications and documents

  • Missouri state-level controlled substance registration applications can only be submitted online, and the applicant may verify status after submission.

    Applies when: For Missouri BNDD state-controlled-substance registration applications.

    Source evidence
    1. 1. health.mo.gov ↗
      applications for a Missouri state-level controlled substance registration can only be submitted online.
    2. 2. health.mo.gov ↗
      After successfully submitting the application and associated fee, the applicant can verify status by clicking Print Certificate or Verify Registration.

  • If the practitioner has multiple practice locations, DEA requires a separate registration for each principal place of business or professional practice.

    Applies when: For federal DEA registration steps tied to practice location.

    Source evidence
    1. 1. deadiversion.usdoj.gov ↗
      A separate registration is required for each principal place of business or professional practice at one general physical location

Authorities and sources †

  • The Bureau of Narcotics and Dangerous Drugs is within DHSS and regulates legitimate medical controlled substance activities in Missouri.

    Applies when: For Missouri controlled-substance authority.

    Source evidence
    1. 1. health.mo.gov ↗
      The Bureau of Narcotics and Dangerous Drugs (BNDD) is the entity within the Department of Health and Senior Services (DHSS) tasked with regulating legitimate medical controlled substance activities

  • The Missouri Board of Nursing is the state nursing-board source for collaborative practice information.

    Applies when: For Missouri nursing-board authority materials.

    Source evidence
    1. 1. pr.mo.gov ↗
      # Board of Nursing ### Nursing & Collaborative Practice
  • †

    Could not confirm from the available official evidence.